Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
VEGFA | P15692 | vascular endothelial growth factor A | Signaling | 2.4E-05 | 0.266 | 0.923 |
VCAN | P13611 | versican | Extracellular structure | 1.00 | 0.497 | 0.808 |
TYMP | P19971 | thymidine phosphorylase | Enzyme | 1.2E-04 | 0.495 | 0.769 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
SRD5A2 | P31213 | steroid 5 alpha-reductase 2 | Enzyme | 0.564 | 0.615 | |
SIRT1 | Q96EB6 | sirtuin 1 | Epigenetic regulator | 8.7E-02 | 0.378 | 0.885 |
S100A8 | P05109 | S100 calcium binding protein A8 | Calcium-binding protein | 0.14 | 0.430 | 0.962 |
RUNX3 | Q13761 | RUNX family transcription factor 3 | Transcription factor | 0.84 | 0.459 | 0.731 |
RARB | P10826 | retinoic acid receptor beta | Nuclear receptor | 1.00 | 0.478 | 0.846 |
PTGS2 | P35354 | prostaglandin-endoperoxide synthase 2 | Enzyme | 1.00 | 0.314 | 0.962 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
PPIA | P62937 | peptidylprolyl isomerase A | 0.56 | 0.510 | 0.769 | |
PGR | P06401 | progesterone receptor | Nuclear receptor | 5.1E-02 | 0.426 | 0.885 |
NR5A1 | Q13285 | nuclear receptor subfamily 5 group A member 1 | Nuclear receptor | 0.99 | 0.479 | 0.731 |
NR4A1 | P22736 | nuclear receptor subfamily 4 group A member 1 | Nuclear receptor | 0.37 | 0.490 | 0.731 |
NFKB1 | P19838 | nuclear factor kappa B subunit 1 | Transcription factor | 1.00 | 0.396 | 0.923 |
MYC | P01106 | MYC proto-oncogene, bHLH transcription factor | Transcription factor | 1.00 | 0.344 | 0.923 |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
MMP9 | P14780 | matrix metallopeptidase 9 | Enzyme | 1.9E-17 | 0.305 | 0.923 |
MMP2 | P08253 | matrix metallopeptidase 2 | Enzyme | 0.84 | 0.333 | 0.923 |
LEPR | P48357 | leptin receptor | Signaling | 0.99 | 0.433 | 0.808 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
ITGB1 | P05556 | integrin subunit beta 1 | Receptor | 0.98 | 0.496 | 0.808 |
IL6 | P05231 | interleukin 6 | 0.32 | 0.248 | 0.962 |